About 5am on Tuesday, officers from Chifley Police District attended a home on Gold Street in Mandurama to speak with the occupant about a domestic violence related matter.

The occupant locked himself inside the premises and refused to speak with police.

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About 7.20am, smoke was detected and soon after, the home was seen to be well alight. Officers forced entry to the home; however, were overcome by the smoke.

Entry was gained via the back door and the occupant, a 46-year-old man, was arrested after being found hiding inside.

The NSW Rural Fire Service and Fire and Rescue NSW attended and extinguished the blaze; however, the home was destroyed.

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NSW Ambulance paramedics attended and treated the man for smoke inhalation. He has been taken to Orange Hospital under police guard for further treatment.

A number of officers were also treated for smoke inhalation.

Inquiries continue.

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Anyone with information about this incident is urged to contact Crime Stoppers on 1800 333 000.

Information is treated in strict confidence. The public is reminded not to report crime via NSW Police social media pages.

MAP: The location of Gold Street, Mandurama