Western NSW Local Health District confirmed the positive cases, with fever clinics established at Orange, Bathurst and Dubbo, with plans being activated at all facilities to cater for changes in demand.

However, to maintain privacy and confidentiality, the locations of confirmed COVID-19 cases are not being made public.

The news comes in light of substantial speculation, and the rapidly changing situation to manage COVID-19.

According to a spokesperson from the Western NSW LHD, these individuals acted in accordance with advice on self-isolation, and as a result there were no contacts identified as being at risk.

They will remain in isolation until deemed no longer infectious following strict public health guidelines.

None of the confirmed cases have visited Orange Hospital, which, other than reasonable steps being implemented in response to COVID-19, continues to operate as normal.

Anyone with concerns about COVID-19 can contact healthdirect on 1800 022 222 and speak to a registered nurse to discuss their symptoms.

Anyone intending to go to their doctor or a hospital emergency department with concerns about COVID-19 should call in advance.

It is expected that responding to COVID-19 will increase hospital activity across the District.

The Western NSW Local Health District has a committed workforce who will work with their local communities and other health care providers, including general practitioners, to minimise the impact of COVID-19.

Meanwhile, a Katoomba High School has been closed to students and staff on Friday following a positive test for coronavirus.

In an announcement last on Thursday night the school advised that a "member of the school community has returned a positive test COVID-19".

"To provide time for NSW Health to conduct their contact tracing process the school will be non-operational Friday, March 13," the school said.

Students and staff have been told to self-isolate for the next few days while authorities trace anyone who has contact with the infected person.

The school did not specify whether it was a student or staff member who had tested positive for coronavirus.

The school said staff and students will be contacted and advised if they can resume school as normal on Monday, March 16, or if a further quarantine period will be required.

The Department of Education said it was working closely with NSW Health to monitor and respond to developments and to ensure the safety and wellbeing of students and staff across the state.

"Consistent with current guidelines, children, students and staff who are unwell with respiratory illness should remain at home until symptoms resolve," the department said.

"In accordance with our current practice if any student becomes unwell we will implement our infection control guidelines and follow the advice provided by NSW Health as appropriate."